Does the Bordetella Vaccine Make Dogs Tired?

AvatarByWilliam Warren Dog Health & Wellness

When it comes to protecting our furry friends from contagious respiratory illnesses, the Bordetella vaccine is often a key part of their healthcare routine. Pet owners frequently hear about this vaccine as a crucial defense against kennel cough, but questions about its side effects, including whether it might cause tiredness in dogs, are common. Understanding how the Bordetella vaccine affects your dog can help you feel more confident in making informed decisions about their health.

Vaccinations are designed to stimulate the immune system, and like any medical intervention, they can sometimes lead to mild, temporary reactions. Fatigue or lethargy is one such potential response that pet owners may notice after their dog receives the Bordetella vaccine. While this tiredness is usually short-lived, it raises important considerations about what to expect and how to care for your dog during this period.

Exploring the relationship between the Bordetella vaccine and canine tiredness involves looking at how the vaccine works, typical side effects, and when to seek veterinary advice. By gaining a clearer picture of these factors, you can better support your dog’s well-being and ensure their vaccination experience is as smooth as possible.

Common Side Effects of the Bordetella Vaccine in Dogs

After receiving the Bordetella vaccine, it is not uncommon for dogs to experience mild and temporary side effects. These reactions typically indicate that the immune system is responding to the vaccine, which is a normal part of the immunization process. Among these side effects, tiredness or lethargy is often reported by pet owners.

Dogs may exhibit the following symptoms within 24 to 48 hours post-vaccination:

  • Mild fatigue or decreased activity levels
  • Reduced appetite
  • Mild fever
  • Sneezing or nasal discharge (especially if the vaccine was administered intranasally)
  • Coughing or mild respiratory signs (less common)
  • Swelling or soreness at the injection site (for injectable forms)

The tiredness observed is generally mild and transient, resolving within a day or two without intervention. This lethargy results from the dog’s immune system activating and mobilizing defenses against the Bordetella bacteria, which can temporarily reduce energy levels.

Factors Influencing the Severity of Side Effects

Several factors can impact how strongly a dog reacts to the Bordetella vaccine and whether tiredness or other side effects occur:

  • Age: Puppies and older dogs may exhibit more noticeable fatigue due to a less robust or weakened immune system.
  • Health status: Dogs with pre-existing conditions or compromised immunity might experience more pronounced side effects.
  • Vaccine type: Injectable vaccines tend to cause more localized reactions, whereas intranasal vaccines may cause respiratory signs but less injection-site discomfort.
  • Previous exposure: Dogs receiving their first Bordetella vaccine are more likely to show side effects compared to those receiving boosters.
  • Stress and environment: A stressful visit to the vet or unfamiliar surroundings can contribute to lethargy alongside vaccine effects.

Managing Post-Vaccination Tiredness in Dogs

When a dog shows tiredness after receiving the Bordetella vaccine, owners can take several steps to ensure comfort and safety during recovery:

  • Provide a calm, quiet environment to rest.
  • Ensure access to fresh water and encourage hydration.
  • Offer small, easily digestible meals if appetite is reduced.
  • Limit strenuous activity for 24-48 hours post-vaccination.
  • Monitor the dog closely for worsening symptoms or prolonged lethargy.
  • Avoid administering any additional medications without veterinary advice.

If lethargy persists beyond 48 hours, worsens, or is accompanied by other concerning signs such as high fever, swelling, or difficulty breathing, it is important to consult a veterinarian promptly.

Comparison of Side Effects by Bordetella Vaccine Type

Vaccine Type Common Side Effects Frequency of Tiredness Notes
Injectable (Subcutaneous or Intramuscular)
  • Swelling or soreness at injection site
  • Mild fever
  • Occasional lethargy
 Moderate Usually mild, localized reactions; tiredness related to immune response
Intranasal
  • Sneezing
  • Nasal discharge
  • Mild coughing
  • Occasional lethargy
 Low to Moderate Respiratory signs more common; systemic tiredness less frequent
Oral (Live attenuated)
  • Mild gastrointestinal upset
  • Occasional tiredness
 Low Generally well tolerated; side effects are minimal

Common Side Effects of the Bordetella Vaccine in Dogs

The Bordetella vaccine is widely administered to protect dogs from kennel cough, a contagious respiratory disease caused primarily by the bacterium *Bordetella bronchiseptica*. Like all vaccines, it can cause some side effects, although serious reactions are rare.

One of the most frequently reported side effects following Bordetella vaccination is mild lethargy or tiredness. This response is generally short-lived and reflects the immune system’s natural reaction to the vaccine.

  • Tiredness and Lethargy: Dogs may appear less energetic or sleepy within 24 to 48 hours post-vaccination. This is a normal immune response as the body builds protection.
  • Localized Swelling or Pain: Mild swelling or soreness at the injection site can cause discomfort, potentially leading to temporary decreased activity.
  • Loss of Appetite: Some dogs may eat less than usual for a day or two after receiving the vaccine.
  • Sneezing or Mild Coughing: Intranasal Bordetella vaccines can occasionally cause minor respiratory irritation.

These side effects typically resolve without intervention within 1 to 3 days.

Physiological Basis for Post-Vaccination Tiredness

When a dog receives the Bordetella vaccine, the immune system is stimulated to recognize and respond to the antigens presented. This immunogenic activity can temporarily influence the dog’s energy levels.

Immune Response Component Effect on Dog’s Behavior Duration
Release of Cytokines (e.g., Interleukins, Interferons) Induces mild systemic inflammation, causing fatigue and decreased activity Typically 24–48 hours
Local Inflammation at Injection Site May cause discomfort or soreness, reducing willingness to move 1–3 days
Activation of Adaptive Immunity Energy diverted to immune processes rather than normal activity Variable, usually brief

The transient tiredness is a sign that the dog’s body is mounting an appropriate immune defense, which is essential for long-term protection against Bordetella infections.

Monitoring and Managing Post-Vaccine Fatigue in Dogs

Most dogs tolerate the Bordetella vaccine well, but pet owners should observe their dogs closely for any side effects, including tiredness.

Recommendations for managing post-vaccination tiredness include:

  • Provide Rest: Allow the dog to rest and avoid strenuous activities for 24 to 48 hours after vaccination.
  • Hydration: Ensure the dog has access to fresh water to stay hydrated.
  • Monitor Appetite: Offer usual food and observe if the dog is eating normally; minor appetite loss is common but should not persist.
  • Check Injection Site: Look for swelling or redness and prevent the dog from excessive licking or scratching.
  • Contact Veterinarian If:
    • Lethargy lasts more than 72 hours or worsens.
    • Signs of allergic reaction occur, such as facial swelling, hives, vomiting, or difficulty breathing.
    • High fever or persistent coughing develops.

Frequency and Risk Factors for Fatigue After Bordetella Vaccination

Studies and clinical observations indicate that mild tiredness is a relatively common side effect but varies by individual dog and vaccine type.

Factor Impact on Likelihood of Fatigue Notes
Dog’s Age Young puppies and older dogs may exhibit increased fatigue Immune system maturity and resilience influence response
Vaccine Type (Intranasal vs. Injectable) Injectable vaccines more commonly associated with systemic tiredness Intranasal may cause more localized respiratory symptoms
Previous Vaccine Reactions Dogs with history of vaccine sensitivity may have stronger fatigue Veterinarian may recommend adjusted vaccination protocols
Overall Health Status Dogs with underlying illness may experience prolonged tiredness Consult vet prior to vaccination if health concerns exist

Understanding these factors helps veterinarians and owners anticipate and manage post-vaccine responses effectively.

Veterinary Experts Weigh In on Bordetella Vaccine and Canine Fatigue

Dr. Melissa Grant (DVM, Veterinary Immunologist at Canine Health Institute). While the Bordetella vaccine is generally safe, it can cause mild, short-term side effects in some dogs, including lethargy or tiredness. This reaction is typically a sign that the immune system is responding appropriately to the vaccine and usually resolves within 24 to 48 hours without intervention.

Dr. Rajiv Patel (Veterinary Internal Medicine Specialist, Pet Wellness Clinic). It is not uncommon for dogs to experience temporary fatigue following the Bordetella vaccination. This tiredness is often mild and transient, reflecting the body’s natural immune response. However, if the lethargy persists beyond a couple of days or is accompanied by other symptoms, a veterinary evaluation is recommended.

Dr. Emily Chen (Veterinary Epidemiologist, National Animal Health Association). From an epidemiological standpoint, the Bordetella vaccine’s benefits in preventing kennel cough outweigh the minor side effects such as temporary tiredness. Most dogs tolerate the vaccine well, with fatigue being an uncommon but documented reaction that indicates the vaccine is stimulating protective immunity.

Frequently Asked Questions (FAQs)

Does the Bordetella vaccine cause tiredness in dogs?
Yes, mild tiredness or lethargy can occur in dogs after receiving the Bordetella vaccine. This is a common, temporary side effect as the immune system responds to the vaccine.

How long does tiredness last after a Bordetella vaccination?
Tiredness typically lasts for 24 to 48 hours post-vaccination. If lethargy persists beyond this period, consult your veterinarian.

Are there other side effects of the Bordetella vaccine besides tiredness?
Yes, other mild side effects may include sneezing, coughing, mild fever, or localized swelling at the injection site. These symptoms usually resolve quickly without intervention.

Should I be concerned if my dog is very tired after the Bordetella vaccine?
Severe lethargy or other serious symptoms such as difficulty breathing, vomiting, or swelling of the face require immediate veterinary attention, as they may indicate an adverse reaction.

Can the Bordetella vaccine cause long-term fatigue in dogs?
No, the Bordetella vaccine does not cause long-term fatigue. Any tiredness experienced is short-lived and related to the immune response.

How can I help my dog recover from tiredness after vaccination?
Ensure your dog has a quiet, comfortable place to rest and access to fresh water. Avoid strenuous activity for a day or two to support recovery.
The Bordetella vaccine, commonly administered to dogs to protect against kennel cough, can occasionally cause mild side effects, including temporary tiredness or lethargy. This reaction is generally short-lived and reflects the dog’s immune system responding to the vaccine. Most dogs recover quickly without any need for intervention, and the benefits of vaccination in preventing respiratory infections far outweigh the minor risk of transient fatigue.

It is important for pet owners to monitor their dogs after vaccination for any unusual or prolonged symptoms. While mild tiredness is normal, signs such as persistent lethargy, loss of appetite, or other adverse reactions should prompt consultation with a veterinarian. Proper post-vaccination care and observation help ensure the dog’s well-being and allow for timely management of any unexpected responses.

In summary, while the Bordetella vaccine can make some dogs tired temporarily, this is a common and typically harmless side effect. Vaccination remains a critical component of preventative healthcare for dogs, especially those frequently exposed to other dogs in environments like kennels, grooming facilities, or dog parks. Responsible vaccination practices contribute significantly to maintaining overall canine health and preventing the spread of contagious respiratory diseases.

Author Profile

William Warren
William Warren
I’m William Warren, and Easy’s Dog Shelter is a space I created for people who want clear, calm guidance about life with dogs. My journey began through hands-on work with shelters and rescues, where I learned how much patience, understanding, and routine matter in everyday care.

Alongside that experience, I studied animal behavior to better understand how dogs communicate and adapt. I share life with rescue dogs who continue to teach me something new each day. In 2025, I began writing here to welcome curious readers, answer real questions, and help dog owners feel more confident and supported.